From: Robina Suwol
Date: 02 Apr 2003
Remote Name: 220.127.116.11
31 March 2003
Many spontaneous miscarriages and birth defects in people, including Down Syndrome, are caused by an error in cell division called aneuploidy. After an accident in two of the world's leading laboratories investigating aneuploidy caused a dramatic increase in this chromosomal error in the lab's mice, careful study revealed that it had been caused by inadvertent contamination by the plastic molecule bisphenol A.
Subsequent work, reported in new paper in Current Biology, then demonstrated that even very low levels of bisphenol A interfered with cell division. These results open a new window into understanding the cause of human birth defects, and significantly heighten pressure to reduce human exposures to bisphenol A.